Detecting differentially methylated regions using a fast wavelet-based approach to functional association analysis

Detecting differentially methylated regions using a fast wavelet-based approach to functional association analysis

Background: We present here a computational shortcut to improve a powerful wavelet-based method by Shim and Stephens (Ann Appl Stat 9(2):665–686, 2015. https://doi.org/10.1214/14-AOAS776) called WaveQTL that was originally designed to identify DNase I hypersensitivity quantitative trait loci (dsQTL)...

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Bibliographic Details
Main Authors: Denault, W.R.P (Author), Jugessur, A. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Alkylation
Association analysis
Bayes theorem
Bayes Theorem
Bioinformatics
Colorectal cancer
Computational speed
computer simulation
Computer Simulation
Diseases
DNA methylation
DNA Methylation
Epigenetics
EWAS
Functional associations
HTTP
phenotype
Phenotype
Public repositories
Quantitative Trait Loci
quantitative trait locus
Quantitative trait locus
Simulation based approaches
Wavelet analysis
Wavelet-based approach
Wavelet-based methods
Wavelets
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