MSIFinder: a python package for detecting MSI status using random forest classifier

MSIFinder: a python package for detecting MSI status using random forest classifier

Background: Microsatellite instability (MSI) is a common genomic alteration in colorectal cancer, endometrial carcinoma, and other solid tumors. MSI is characterized by a high degree of polymorphism in microsatellite lengths owing to the deficiency in the mismatch repair system. Based on the degree,...

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Bibliographic Details
Main Authors: Cao, S. (Author), Chen, L. (Author), Guo, J. (Author), Lou, F. (Author), Wang, H. (Author), Zhang, M. (Author), Zhang, Y. (Author), Zhou, T. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Area under the curves
Classification (of information)
Colorectal Neoplasms
colorectal tumor
Computational approach
Decision trees
Diseases
DNA Mismatch Repair
DNA sequences
Endometrial carcinomas
genetics
Genome sequencing
High level languages
human
Humans
Immunotherapy
Machine learning technology
microsatellite DNA
microsatellite instability
Microsatellite instability
Microsatellite Instability
Microsatellite Repeats
mismatch repair
Mismatch repair systems
Positive predictive values
Prospective Studies
prospective study
Random forest classifier
Random forests
Satellites
Tumors
Turing machines
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