A base measure of precision for protein stability predictors: structural sensitivity
Background: Prediction of the change in fold stability (ΔΔG) of a protein upon mutation is of major importance to protein engineering and screening of disease-causing variants. Many prediction methods can use 3D structural information to predict ΔΔG. While the performance of these methods has been e...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BioMed Central Ltd
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |