A new algorithm to train hidden Markov models for biological sequences with partial labels

Background: Hidden Markov models (HMM) are a powerful tool for analyzing biological sequences in a wide variety of applications, from profiling functional protein families to identifying functional domains. The standard method used for HMM training is either by maximum likelihood using counting when...

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Bibliographic Details
Main Authors: Lee, J.-Y (Author), Li, J. (Author), Liao, L. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Online Access:View Fulltext in Publisher