scSensitiveGeneDefine: sensitive gene detection in single-cell RNA sequencing data by Shannon entropy

scSensitiveGeneDefine: sensitive gene detection in single-cell RNA sequencing data by Shannon entropy

Background: Single-cell RNA sequencing (scRNA-seq) is the most widely used technique to obtain gene expression profiles from complex tissues. Cell subsets and developmental states are often identified via differential gene expression patterns. Most of the single-cell tools utilized highly variable g...

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Bibliographic Details
Main Authors: Chen, Z. (Author), Hao, P. (Author), Yang, Z. (Author), Yuan, X. (Author), Zhang, X. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Cellular stress response
Clustering algorithms
Coefficients of variations
Cytology
Differential gene expressions
Environmental stimuli
Gene expression
Gene expression profiles
gene expression profiling
Gene Expression Profiling
Histology
human
Humans
reproducibility
Reproducibility of Results
RNA
Sensitive genes
sequence analysis
Sequence Analysis, RNA
single cell analysis
Single-Cell Analysis
Single-cell RNA sequencing
Stochastic gene expression
Stochastic gene expressions
Stochastic systems
Tissue
Unsupervised clustering
Unsupervised clustering algorithm
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