Profile hidden Markov model sequence analysis can help remove putative pseudogenes from DNA barcoding and metabarcoding datasets

Background: Pseudogenes are non-functional copies of protein coding genes that typically follow a different molecular evolutionary path as compared to functional genes. The inclusion of pseudogene sequences in DNA barcoding and metabarcoding analysis can lead to misleading results. None of the most...

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Bibliographic Details
Main Authors: Hajibabaei, M. (Author), Porter, T.M (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
DNA
Online Access:View Fulltext in Publisher