An effective method to resolve ambiguous bisulfite-treated reads

Background: The combination of the bisulfite treatment and the next-generation sequencing is an important method for methylation analysis, and aligning the bisulfite-treated reads (BS-reads) is the critical step for the downstream applications. As bisulfite treatment reduces the complexity of the se...

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Bibliographic Details
Main Authors: Liu, M. (Author), Xu, Y. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
DNA
Online Access:View Fulltext in Publisher