PPalign: optimal alignment of Potts models representing proteins with direct coupling information

Background: To assign structural and functional annotations to the ever increasing amount of sequenced proteins, the main approach relies on sequence-based homology search methods, e.g. BLAST or the current state-of-the-art methods based on profile Hidden Markov Models, which rely on significant ali...

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Bibliographic Details
Main Authors: Coste, F. (Author), Talibart, H. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Online Access:View Fulltext in Publisher