Putative markers for the detection of early-stage bladder cancer selected by urine metabolomics

Putative markers for the detection of early-stage bladder cancer selected by urine metabolomics

Background: Early detection of bladder cancer remains challenging because patients with early-stage bladder cancer usually have no incentive to take cytology or cystoscopy tests if they are asymptomatic. Our goal is to find non-invasive marker candidates that may help us gain insight into the metabo...

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Bibliographic Details
Main Authors: Chen, C.-L (Author), Chen, Y.-T (Author), Fu, S.-H (Author), Juo, B.-R (Author), Lin, J.-Y (Author), Wu, K.-P (Author), Yeh, Y.-H (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Alcohols
Bioinformatics
Biomarkers
Biomarkers, Tumor
Bladder cancers
bladder tumor
Bonferroni correction
Cancer patients
Cytology
Diseases
Gas chromatography
Gas chromatography-mass spectrometry
Gas Chromatography-Mass Spectrometry
human
Humans
Leave-one-out cross validations
mass fragmentography
Mass spectrometry
Metabolic profiles
Metabolism
Metabolites
metabolome
Metabolome
metabolomics
Metabolomics
Omics data analysis
Patient monitoring
Polyols
Putative metabolites
Statistical methods
Sugars
tumor marker
Urinary Bladder Neoplasms
Wilcoxon rank sum test
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