The expression landscape of JAK1 and its potential as a biomarker for prognosis and immune infiltrates in NSCLC

The expression landscape of JAK1 and its potential as a biomarker for prognosis and immune infiltrates in NSCLC

Background: Janus-activated kinase-1 (JAK1) plays a crucial role in many aspects of cell proliferation, differentiation, apoptosis and immune regulation. However, correlations of JAK1 with prognosis and immune infiltration in NSCLC have not been documented. Methods: We analyzed the relationship betw...

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Bibliographic Details
Main Authors: Fan, M. (Author), Jiang, X. (Author), Lu, W. (Author), Lu, Z. (Author), Lv, T. (Author), Shen, K. (Author), Song, Y. (Author), Wang, X. (Author), Wei, Y. (Author), Zhan, P. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Biomarkers, Tumor
Carcinoma, Non-Small-Cell Lung
Cell death
Cell proliferation
Cell proliferation/differentiation
Diagnosis
genetics
human
Humans
Immune infiltrating
JAK1
JAK1 protein, human
Janus kinase 1
Janus Kinase 1
Janus-activated kinase
Janus-activated kinase-1
Kaplan Meier method
Kaplan-Meier Estimate
Lung Neoplasms
lung tumor
Lymphocytes, Tumor-Infiltrating
male
Male
non small cell lung cancer
Normal tissue
NSCLC
Overexpressions
Pathology
Prognose
Prognosis
Public database
Squamous cell carcinoma
T-cells
tumor associated leukocyte
tumor marker
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