Identifying piRNA targets on mRNAs in C. elegans using a deep multi-head attention network

Identifying piRNA targets on mRNAs in C. elegans using a deep multi-head attention network

Background: Piwi-interacting RNAs (piRNAs) are the small non-coding RNAs (ncRNAs) that silence genomic transposable elements. And researchers found out that piRNA also regulates various endogenous transcripts. However, there is no systematic understanding of the piRNA binding patterns and how piRNA...

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Bibliographic Details
Main Authors: Chen, K.-Y (Author), Shiue, S.-C (Author), Tseng, Y.-Y (Author), Wu, W.-S (Author), Yang, T.-H (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
animal
Animals
argonaute protein
Argonaute Proteins
Binding pattern
Binding sites
Caenorhabditis elegans
Caenorhabditis elegans protein
Caenorhabditis elegans Proteins
CLASH
Deep learning
DNA Transposable Elements
Elegans
Forecasting
genetics
Learning methods
messenger RNA
Messenger RNA
microRNA
MicroRNAs
Multi-head attention
piRNA
PiRNA
PRG-1 protein, C elegans
RNA binding
RNA, Messenger
RNA, Small Interfering
small interfering RNA
Subnetworks
transposon
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