Filling gaps of genome scaffolds via probabilistic searching optical maps against assembly graph
Background: Optical maps record locations of specific enzyme recognition sites within long genome fragments. This long-distance information enables aligning genome assembly contigs onto optical maps and ordering contigs into scaffolds. The generated scaffolds, however, often contain a large amount o...
Main Authors: | Bu, D. (Author), Huang, B. (Author), Ju, F. (Author), Shi, Z. (Author), Sun, S. (Author), Wang, B. (Author), Wei, G. (Author), Zhong, Y. (Author) |
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Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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