Exploring cell-specific miRNA regulation with single-cell miRNA-mRNA co-sequencing data

Exploring cell-specific miRNA regulation with single-cell miRNA-mRNA co-sequencing data

Background: Existing computational methods for studying miRNA regulation are mostly based on bulk miRNA and mRNA expression data. However, bulk data only allows the analysis of miRNA regulation regarding a group of cells, rather than the miRNA regulation unique to individual cells. Recent advance in...

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Bibliographic Details
Main Authors: Le, T.D (Author), Li, J. (Author), Li, S. (Author), Liu, L. (Author), Rao, N. (Author), Xu, T. (Author), Zhang, J. (Author), Zhang, W. (Author), Zhao, C. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Cell clustering
Cell cross talks
Cell–cell crosstalk
Cells
Cell-specific miRNA regulation
Chronic myelogenous leukemia
Chronic Myelogenous Leukemia
cluster analysis
Cluster Analysis
Clustering analysis
Crosstalk
Cytology
gene expression profiling
Gene Expression Profiling
gene regulatory network
Gene Regulatory Networks
genetics
messenger RNA
microRNA
MicroRNAs
miRNA
mRNA
MRNA
Pseudo-cell interpolation
RNA
RNA, Messenger
Single cells
Single-cell clustering analyse
Single-cell clustering analysis
Single-cell miRNA-mRNA co-sequencing
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