gcMECM: graph clustering of mutual exclusivity of cancer mutations

gcMECM: graph clustering of mutual exclusivity of cancer mutations

Background: Next-generation sequencing platforms allow us to sequence millions of small fragments of DNA simultaneously, revolutionizing cancer research. Sequence analysis has revealed that cancer driver genes operate across multiple intricate pathways and networks with mutations often occurring in...

Full description

Bibliographic Details
Main Authors: Chen, Q. (Author), Hu, Y. (Author), Meerzaman, D. (Author), Yan, C. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
algorithm
article
Association reactions
Bioinformatics
Cancer driver gene
Cancer driver genes
cancer model
Cancer research
clinical evaluation
Diseases
Gene encoding
gene interaction
Graph clustering
human
Lower frequencies
Mutual exclusivities
Mutually exclusive mutation
Mutually exclusive mutations
network analysis
Network analysis
Next-generation sequencing
R package
Sequence analysis
Subnetworks
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items