KnotAli: informed energy minimization through the use of evolutionary information

Background: Improving the prediction of structures, especially those containing pseudoknots (structures with crossing base pairs) is an ongoing challenge. Homology-based methods utilize structural similarities within a family to predict the structure. However, their prediction is limited to the cons...

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Bibliographic Details
Main Authors: Chester, S. (Author), Gray, M. (Author), Jabbari, H. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
MFE
RNA
Online Access:View Fulltext in Publisher