A longitudinal analysis of immune escapes from HLA-B*13-restricted T-cell responses at early stage of CRF01_AE subtype HIV-1 infection and implications for vaccine design

Background: Identifying immunogens which can elicit effective T cell responses against human immunodeficiency virus type 1 (HIV-1) is important for developing a T-cell based vaccine. It has been reported that human leukocyte antigen (HLA)-B*13-restricted T-cell responses contributed to HIV control i...

Full description

Bibliographic Details
Main Authors:	Cao, S. (Author), Ding, H. (Author), Dong, T. (Author), Han, X. (Author), He, C. (Author), Jiang, F. (Author), Shang, H. (Author), Zhang, H. (Author), Zhao, B. (Author)
Format:	Article
Language:	English
Published:	BioMed Central Ltd 2022
Subjects:	antigenic escape Article CD4 lymphocyte count cell isolation clinical article cohort analysis controlled study CRF01_AE cross reaction disease course disease duration drug design enzyme linked immunospot assay epitope Epitope Escape mutation gamma interferon gene mutation gene sequence genetic variability high risk patient HIV Infections HIV-1 HLA B antigen HLA B13 antigen HLA typing HLA-B Antigens HLA-B*13 Homosexuality, Male human human cell Human immunodeficiency virus 1 Human immunodeficiency virus 1 infection Human immunodeficiency virus gag protein Human immunodeficiency virus infection Human immunodeficiency virus vaccine Humans infection control longitudinal study male Male male homosexuality men who have sex with men molecular cloning pathogenesis peripheral blood mononuclear cell physiology population structure Sexual and Gender Minorities sexual and gender minority T lymphocyte T-cell response T-Lymphocytes virus load virus RNA
Online Access:	View Fulltext in Publisher

Internet

View Fulltext in Publisher

A longitudinal analysis of immune escapes from HLA-B*13-restricted T-cell responses at early stage of CRF01_AE subtype HIV-1 infection and implications for vaccine design

Internet

Similar Items