Nuclear respiratory factor 1 promotes the growth of liver hepatocellular carcinoma cells via E2F1 transcriptional activation

Background: Recent studies have shown that functional mitochondria are essential for cancer cells. Nuclear respiratory factor 1 (NRF1) is a transcription factor that activates mitochondrial biogenesis and the expression of the respiratory chain, but little is known about its role and underlying mech...

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Bibliographic Details
Main Authors: Liu, C. (Author), Lu, S. (Author), Sun, P. (Author), Wan, B. (Author), Wang, D. (Author), Zhang, X. (Author), Zhu, L. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
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