A comparison of clinical pathologic characteristics between alpha-fetoprotein negative and positive hepatocellular carcinoma patients from Eastern and Southern China

A comparison of clinical pathologic characteristics between alpha-fetoprotein negative and positive hepatocellular carcinoma patients from Eastern and Southern China

Background: Alpha-fetoprotein (AFP) is a biomarker used in clinical management of hepatocellular carcinoma (HCC), however, approximately 40% of HCC patients do not present with elevated serum AFP levels. This study aimed to investigate the clinical and pathologic characteristics between AFP positive...

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Bibliographic Details
Main Authors: Chi, X. (Author), Hochwald, S. (Author), Huang, H. (Author), Huang, X. (Author), Jiang, L. (Author), Liu, J. (Author), Yang, X. (Author), Yuan, Y. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
alpha fetoprotein
Alpha-fetoprotein (AFP)
alpha-Fetoproteins
bilirubin
Bilirubin
biological marker
Biomarkers
Biomarkers, Tumor
Carcinoembryonic antigen (CEA)
Carcinoma, Hepatocellular
Chronic hepatitis B
gamma glutamyltransferase
gamma-Glutamyltransferase
Hepatitis B virus DNA (HBV DNA)
Hepatocellular carcinoma (HCC)
human
Humans
liver cell carcinoma
liver cirrhosis
Liver cirrhosis
Liver Cirrhosis
Liver Neoplasms
liver tumor
metabolism
Neutrophil to lymphocyte ratio (NLR)
pathology
Protein induced vitamin K absence or antagonist-II (PIVKA-II)
protein precursor
Protein Precursors
prothrombin
Prothrombin
receiver operating characteristic
ROC Curve
tumor marker
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