BIRC5 regulates inflammatory tumor microenvironment-induced aggravation of penile cancer development in vitro and in vivo

BIRC5 regulates inflammatory tumor microenvironment-induced aggravation of penile cancer development in vitro and in vivo

Background: Baculoviral IAP repeat containing 5 (BIRC5) is overexpressed and plays as a key regulator in the progression of various human carcinomas. The inflammatory tumor microenvironment (ITM) is closely associated with the development of cancers. However, the role of BIRC5 in penile cancer (PC)...

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Bibliographic Details
Main Authors: Li, S. (Author), Liu, S. (Author), Tian, A. (Author), Wan, Y. (Author), Zhang, G. (Author), Zhao, Y. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
animal
Animals
baculoviral IAP repeat containing protein 5
BIRC5
BIRC5 protein, human
Cell Line, Tumor
cell proliferation
Cell Proliferation
gene expression regulation
Gene Expression Regulation, Neoplastic
genetics
human
Humans
Inflammation
male
Male
Mice
Migration and invasion
mouse
Penile cancer
Penile Neoplasms
penis tumor
Survivin
tumor cell line
tumor microenvironment
Tumor microenvironment
Tumor Microenvironment
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