The frequency and clinical implication of mismatch repair protein deficiency in Chinese patients with ovarian clear cell carcinoma

The frequency and clinical implication of mismatch repair protein deficiency in Chinese patients with ovarian clear cell carcinoma

Background: The aim of the present study was to assess the prevalence of deficient mismatch repair (MMR) in Chinese ovarian clear cell carcinoma (CCC) patients and its association with clinicopathologic features. Methods: Immunohistochemistry with four antibodies against MLH1, PMS2, MSH2 and MSH6 wa...

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Bibliographic Details
Main Authors: Cai, X. (Author), Jiang, W. (Author), Shan, B. (Author), Yang, H. (Author), Yang, W. (Author), Ye, S. (Author), Zhong, S. (Author), Zhou, S. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
adenocarcinoma
Adenocarcinoma, Clear Cell
carcinoma
Carcinoma
China
Clear cell carcinoma
Clinicopathologic relevance
DNA Mismatch Repair
DNA mismatch repair protein MSH2
Endometrial Neoplasms
endometrium tumor
female
Female
genetics
human
Humans
metabolism
middle aged
Middle Aged
mismatch repair
Mismatch repair
Mismatch Repair Endonuclease PMS2
mismatch repair protein PMS2
MutL protein homolog 1
MutL Protein Homolog 1
MutS Homolog 2 Protein
Ovarian carcinoma
pathology
protein deficiency
Protein Deficiency
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