Do hypoxia and L-mimosine modulate sclerostin and dickkopf-1 production in human dental pulp-derived cells? Insights from monolayer, spheroid and tooth slice cultures

Background: To understand the responses of the dental pulp to hypoxia is of high relevance for regenerative endodontics and dental traumatology. Here, we aimed to reveal the effects of hypoxia and the hypoxia mimetic agent L-mimosine (L-MIM) on the production of sclerostin (SOST) and dickkopf-1 (DKK...

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Bibliographic Details
Main Authors: Agis, H. (Author), Cvikl, B. (Author), Janjić, K. (Author), Kurzmann, C. (Author), Moritz, A. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd. 2018
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