Ficus deltoidea ameliorates biochemical, hormonal, and histomorphometric changes in letrozole-induced polycystic ovarian syndrome rats

Ficus deltoidea ameliorates biochemical, hormonal, and histomorphometric changes in letrozole-induced polycystic ovarian syndrome rats

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Background: Insulin resistance and hormonal imbalances are key features in the pathophysiology of polycystic ovarian syndrome (PCOS). We have previously shown that Ficus deltoidea var. deltoidea Jack (Moraceae) can improve insulin sensitivity and hormonal profile in PCOS female rats. However, biolog...

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Bibliographic Details
Main Authors: Goh, Y.M (Author), Hashim, N. (Author), Haslan, M.A (Author), Samsulrizal, N. (Author), Shirazi, F.H (Author), Zin, N.S.N.M (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Series:BMC Complementary Medicine and Therapies
Subjects:
animal experiment
animal model
animal tissue
Antioxidant
antioxidant activity
Article
body mass
cholesterol
clomifene citrate
controlled study
endometrial thickness
enzyme linked immunosorbent assay
estrogen
estrus cycle
female
Ficus
Ficus deltoidea
Ficus deltoidea extract
follitropin
glucose blood level
gonadotropin
high density lipoprotein cholesterol
histology
homeostasis model assessment
insulin resistance
letrozole
Letrozole
Lipid
lipid fingerprinting
low density lipoprotein cholesterol
luteinizing hormone
malonaldehyde
morphometry
nonhuman
obesity
Ovary
ovary polycystic disease
oxidative stress
plant extract
Polycystic ovarian syndrome
progesterone
rat
steroid hormone
superoxide dismutase
testosterone
triacylglycerol
unclassified drug
Uterus
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