Oridonin attenuates low shear stress-induced endothelial cell dysfunction and oxidative stress by activating the nuclear factor erythroid 2-related factor 2 pathway

Oridonin attenuates low shear stress-induced endothelial cell dysfunction and oxidative stress by activating the nuclear factor erythroid 2-related factor 2 pathway

Background: Atherosclerosis (AS) is the primary cause of cardiovascular disease and the incidence is extremely common; however, there are currently few drugs that can effectively treat AS. Although oridonin has been widely used to treat inflammation and cancer for numerous years, to the best of our...

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Bibliographic Details
Main Authors: Cai, J. (Author), Chen, Z. (Author), Liu, C. (Author), Liu, H. (Author), Liu, Y. (Author), Mamateli, S. (Author), Qiao, T. (Author), Wang, L. (Author), Yu, J. (Author), Zhao, X. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Atherosclerosis
Endothelial cell dysfunction
Low shear stress
Nuclear factor erythroid 2-related factor 2
Oridonin
Oxidative stress
Zebrafish
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