FGFR1 is a potential therapeutic target in neuroblastoma

FGFR1 is a potential therapeutic target in neuroblastoma

Background: FGFR1 regulates cell–cell adhesion and extracellular matrix architecture and acts as oncogene in several cancers. Potential cancer driver mutations of FGFR1 occur in neuroblastoma (NB), a neural crest-derived pediatric tumor arising in sympathetic nervous system, but so far they have not...

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Bibliographic Details
Main Authors: Avitabile, M. (Author), Cantalupo, S. (Author), Capasso, M. (Author), Castellano, A. (Author), Cimmino, F. (Author), De Angelis, B. (Author), Iolascon, A. (Author), Lasorsa, V.A (Author), Locatelli, F. (Author), Maiorino, T. (Author), Montella, A. (Author), Morini, M. (Author), Tirelli, M. (Author), Visconte, F. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
FGFR1
Metastasis
Mutation
Neuroblastoma
Targeted therapy
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