Association and mediation analyses among multiple metals exposure, plasma folate, and community-based impaired estimated glomerular filtration rate in central Taiwan

Association and mediation analyses among multiple metals exposure, plasma folate, and community-based impaired estimated glomerular filtration rate in central Taiwan

Background: Chronic kidney disease (CKD) is increasing, with heavy metal exposure an important risk factor. Additionally, the antioxidant folic acid has been studied for reducing blood arsenic levels and related tissue damage. Therefore, we explored the association and mediation effects among variou...

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Bibliographic Details
Main Authors: Chung, C.-J (Author), Chung, M.-C (Author), Ho, C.-T (Author), Hsu, H.-T (Author), Liu, C.-S (Author), Mao, Y.-C (Author), Wu, C.-C (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
adult
Adult
arsenic
Arsenic
cadmium
Cadmium
Chronic kidney disease
chronic kidney failure
Cross-Sectional Studies
cross-sectional study
female
Female
Folate
folic acid
Folic Acid
Glomerular Filtration Rate
glomerulus filtration rate
heavy metal
human
Humans
male
Male
Mediation analysis
Mediation Analysis
Metals
Metals, Heavy
Prospective Studies
prospective study
Renal Insufficiency, Chronic
Taiwan
uric acid
Uric Acid
Weighted quantile sum regression
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