Enhanced status of inflammation and endothelial activation in subjects with familial hypercholesterolaemia and their related unaffected family members: A case control study

Background: Familial hypercholesterolaemia (FH) leads to premature coronary artery diseases (CAD) which pathophysiologically can be measured by inflammation, endothelial activation and oxidative stress status. However, the status of these biomarkers among related unaffected relatives of FH cases and...

Full description

Bibliographic Details
Main Authors:	Hamzan, N.S (Author), Ibrahim, Z.O (Author), Mokhsin, A. (Author), Nawawi, H. (Author), Rahman, T. (Author), Rahmat, R. (Author), Razali, R. (Author), Thevarajah, M. (Author)
Format:	Article
Language:	English
Published:	BioMed Central Ltd. 2017
Subjects:	adult Adult age distribution Article biological marker Biomarkers blood blood sampling body mass C reactive protein case control study Case-Control Studies cell activation Cholesterol, HDL Cholesterol, LDL complication controlled study coronary artery disease Coronary artery disease Coronary Artery Disease C-Reactive Protein diabetes mellitus diet restriction Endothelial activation endothelial leukocyte adhesion molecule 1 endothelium Endothelium, Vascular E-Selectin F2-Isoprostanes Familial hypercholesterolaemia familial hypercholesterolemia family Family family assessment Fasting female Female high density lipoprotein cholesterol human Humans Hyperlipoproteinemia Type II hypertension ICAM1 protein, human inflammation Inflammation intercellular adhesion molecule 1 Intercellular Adhesion Molecule-1 isoprostane derivative lipid analysis Lipoproteins, LDL Logistic Models low density lipoprotein low density lipoprotein cholesterol major clinical study male Male malonaldehyde Malondialdehyde metabolism middle aged Middle Aged oxidative stress Oxidative stress Oxidative Stress oxidized low density lipoprotein pathophysiology protein analysis protein blood level protein function risk factor Risk Factors SELE protein, human sex difference smoking habit statistical model triacylglycerol Triglycerides vascular endothelium
Online Access:	View Fulltext in Publisher View in Scopus

Internet

View Fulltext in Publisher
View in Scopus

Enhanced status of inflammation and endothelial activation in subjects with familial hypercholesterolaemia and their related unaffected family members: A case control study

Internet

Similar Items