Regulatory roles of alternative splicing at Ezh2 gene in mouse oocytes

Regulatory roles of alternative splicing at Ezh2 gene in mouse oocytes

Background: Enhancer of zeste homologue 2 (EZH2), the core member of polycomb repressive complex 2 (PRC2), has multiple splicing modes and performs various physiological functions. However, function and mechanism of alternative splicing at Ezh2 exon 3 in reproduction are unknown. Methods: We generat...

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Bibliographic Details
Main Authors: Fei, C.-F (Author), Guo, S.-M (Author), He, X. (Author), Li, Z.-M (Author), Liu, X.-P (Author), Tian, Q. (Author), Yin, Y. (Author), Zhang, Y.-R (Author), Zhou, L.-Q (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Alternative splicing
Ezh2
Mitochondria
Oocyte
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