Rhein attenuates angiotensin II-induced cardiac remodeling by modulating AMPK–FGF23 signaling

Background: Increasing evidence indicates that myocardial oxidative injury plays a crucial role in the pathophysiology of cardiac hypertrophy (CH) and heart failure (HF). The active component of rhubarb, rhein exerts significant actions on oxidative stress and inflammation. Nonetheless, its role in...

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Bibliographic Details
Main Authors: Cheng, G. (Author), Li, X. (Author), Liao, S. (Author), Lu, W. (Author), Wu, J. (Author), Zhu, H. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
ROS
Online Access:View Fulltext in Publisher