Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy

Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy

Background: The development of diabetes vascular calcification (VC) is tightly associated with the inhibition of vascular smooth muscle cell (VSMC) autophagy. Previously, our team found that miR-32-5p (miR-32) promotes macrophage activation, and miR-32 is expressed at higher level in the plasma of p...

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Bibliographic Details
Main Authors: Cao, J. (Author), Chen, C. (Author), Chen, Q. (Author), Gao, Y. (Author), He, Y. (Author), Li, A. (Author), Liu, J. (Author), Yang, S. (Author), Yuan, Q. (Author), Zhao, Z. (Author), Zu, X. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Diabetes
EVs
Macrophage
miR-32
Vascular calcification
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