Proteomics-based investigation of cerebrovascular molecular mechanisms in cerebral amyloid angiopathy by the FFPE-LMD-PCT-SWATH method

Background: Cerebral amyloid angiopathy (CAA) occurs in 80% of patients with Alzheimer’s disease (AD) and is mainly caused by the abnormal deposition of Aβ in the walls of cerebral blood vessels. Cerebrovascular molecular mechanisms in CAA were investigated by using comprehensive and accurate quanti...

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Bibliographic Details
Main Authors: Handa, T. (Author), Sasaki, H. (Author), Takao, M. (Author), Tano, M. (Author), Uchida, Y. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
CAA
Online Access:View Fulltext in Publisher