Transgenerational effects of paternal heroin addiction on anxiety and aggression behavior in male offspring

Transgenerational effects of paternal heroin addiction on anxiety and aggression behavior in male offspring

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Background: Heroin addiction is a growing concern, affecting the socioeconomic development of many countries. Little is known about transgenerational effects on phenotype changes due to heroin addiction. This study aims to investigate changes in level of anxiety and aggression up to four different g...

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Bibliographic Details
Main Authors: Farah Naquiah, M.Z (Author), James, R.J (Author), Lee, L.S (Author), Mohd Hafidz, M.I (Author), Salleh, M.Z (Author), Suratman, S. (Author), Teh, L.K (Author)
Format: Article
Language:English
Published: BioMed Central Ltd. 2016
Subjects:
adverse effects
aggression
Aggression
animal
animal experiment
animal model
Animals
anxiety
Anxiety
anxiety disorder
Anxiety Disorders
Article
body weight
Body Weight
concentration response
controlled study
diamorphine
drug effects
drug exposure
drug withdrawal
elevated plus maze test
female
Female
genetics
heroin dependence
Heroin Dependence
litter size
male
Male
Male offspring
mating
Maze Learning
maze test
metabolism
motor activity
Motor Activity
nonhuman
open field test
paternal behavior
paternal exposure
Paternal Exposure
Paternal heroin addiction
paternal inheritance
Paternal Inheritance
perinatal period
priority journal
progeny
psychology
rat
Rats
Rats, Sprague-Dawley
resident-intruder test
sodium chloride
Sprague Dawley rat
Transgenerational effects
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