Effect of DACH1 on proliferation and invasion of laryngeal squamous cell carcinoma

Effect of DACH1 on proliferation and invasion of laryngeal squamous cell carcinoma

Background: To investigate the effect of DACH1 over-expression on proliferation and invasion of laryngeal squamous cell carcinoma (LSCC). Methods: The 120 cases of LSCC tumors and 114 adjacent non-neoplastic tissues were collected to detect the expression of DACH1 by immunohistochemistry. The change...

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Bibliographic Details
Main Authors: Cao, J. (Author), Liu, M. (Author), Ren, X. (Author), Tian, L. (Author), Wang, B. (Author), Zhang, J. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd. 2018
Subjects:
aged
Aged
Biopsy, Needle
Blotting, Western
cancer staging
Carcinoma, Squamous Cell
case control study
Case-Control Studies
cell proliferation
Cell Proliferation
comparative study
DACH1
DACH1 protein, human
eye protein
Eye Proteins
female
Female
gene expression regulation
Gene Expression Regulation, Neoplastic
genetics
human
Humans
immunohistochemistry
Immunohistochemistry
Invasion
Laryngeal Neoplasms
larynx tumor
LSCC
male
Male
middle aged
Middle Aged
needle biopsy
Neoplasm Invasiveness
Neoplasm Staging
pathology
prognosis
Prognosis
Proliferation
real time polymerase chain reaction
Real-Time Polymerase Chain Reaction
Retrospective Studies
retrospective study
squamous cell carcinoma
transcription factor
Transcription Factors
tumor invasion
upregulation
Up-Regulation
Western blotting
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