The role of the Smad2/3/4 signaling pathway in osteogenic differentiation regulation by ClC-3 chloride channels in MC3T3-E1 cells

Background: ClC-3 chloride channels promote osteogenic differentiation. Transforming growth factor-β1 (TGF-β1) and its receptors are closely related to ClC-3 chloride channels, and canonical TGF-β1 signaling is largely mediated by Smad proteins. The current study aimed to explore the role of the Sma...

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Bibliographic Details
Main Authors: Cao, M. (Author), Jin, Z. (Author), Li, W. (Author), Lu, X. (Author), Wang, H. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
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Online Access:View Fulltext in Publisher