VCP suppresses proteopathic seeding in neurons
Background: Neuronal uptake and subsequent spread of proteopathic seeds, such as αS (alpha-synuclein), Tau, and TDP-43, contribute to neurodegeneration. The cellular machinery participating in this process is poorly understood. One proteinopathy called multisystem proteinopathy (MSP) is associated w...
Main Authors: | Ayala, Y. (Author), Bieschke, J. (Author), Buscher, W.J (Author), Clemen, C.S (Author), Davis, A.A (Author), Dhavale, D. (Author), Diamond, M.I (Author), French, R. (Author), Kaleelurrrahuman, M.S (Author), Kotzbauer, P. (Author), Maggiore, G. (Author), Patterson, J.N (Author), Pittman, S. (Author), Sun, Y. (Author), Vaquer-Alicea, J. (Author), Weihl, C. (Author), Zhu, J. (Author) |
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Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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