A randomized, double-blind, placebo-controlled study to assess efficacy of mirtazapine for the treatment of diarrhea predominant irritable bowel syndrome

Background: Ample evidence indicates the efficacy of serotonin type 3 (5-HT3) receptor antagonists in the treatment of patients with diarrhea-predominant irritable bowel syndrome (IBS-D). Mirtazapine is an atypical antidepressant with a well-known 5-HT3 receptor antagonist property. This study, ther...

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Bibliographic Details
Main Authors: Ahmadimoghaddam, D. (Author), Khalilian, A. (Author), Mehrpooya, M. (Author), Mohammadi, Y. (Author), Saki, S. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
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Online Access:View Fulltext in Publisher