Prenatal diagnosis and genetic counseling of a paternally inherited chromosome 15q11.2 microdeletion in a Chinese family

Prenatal diagnosis and genetic counseling of a paternally inherited chromosome 15q11.2 microdeletion in a Chinese family

Background: Proximal region of chromosome 15 long arm is rich in duplicons that, define five breakpoints (BP) for 15q rearrangements. 15q11.2 microdeletion has been previously associated with developmental delay, mental retardation, epilepsy, autism, schizophrenia and congenital heart defects. The l...

Full description

Bibliographic Details
Main Authors: Chen, G. (Author), Tang, W. (Author), Xia, J. (Author), Zhang, Y. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
article
case report
Chinese
Chromosomal microarray analysis (CMA)
Chromosomal microdeletions/microduplications
chromosome 15q
clinical article
cytogenetics
deletion mutant
diagnosis
father
fetus
fetus echography
gene deletion
genetic counseling
human
human experiment
karyotyping
male
microarray analysis
paternal inheritance
phenotype
prenatal diagnosis
Prenatal diagnosis
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items