Performance of model-based multifactor dimensionality reduction methods for epistasis detection by controlling population structure
Background: In genome-wide association studies the extent and impact of confounding due to population structure have been well recognized. Inadequate handling of such confounding is likely to lead to spurious associations, hampering replication, and the identification of causal variants. Several str...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BioMed Central Ltd
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |