Indels in SARS-CoV-2 occur at template-switching hotspots

Indels in SARS-CoV-2 occur at template-switching hotspots

The evolutionary dynamics of SARS-CoV-2 have been carefully monitored since the COVID-19 pandemic began in December 2019. However, analysis has focused primarily on single nucleotide polymorphisms and largely ignored the role of insertions and deletions (indels) as well as recombination in SARS-CoV-...

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Bibliographic Details
Main Authors: Chrisman, B.S (Author), Jung, J.-Y (Author), Maleki, S. (Author), Paskov, K. (Author), Stockham, N. (Author), Sun, M.W (Author), Tabatabaei, K. (Author), Varma, M. (Author), Wall, D.P (Author), Washington, P. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Article
coronavirus disease 2019
gene cluster
gene deletion
gene insertion
gene locus
gene replication
gene structure
genetic heterogeneity
genetic recombination
genome
Genomics
indel mutation
nonhuman
prediction
Recombination
RNA directed RNA polymerase
RNA folding
RNA virus
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
transcriptomics
virus genome
virus replication
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