Coupling sparse Cox models with clustering of longitudinal transcriptomics data for trauma prognosis
Background: Longitudinal gene expression analysis and survival modeling have been proved to add valuable biological and clinical knowledge. This study proposes a novel framework to discover gene signatures and patterns in a high-dimensional time series transcriptomics data and to assess their associ...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd
2021
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Subjects: | |
Online Access: | View Fulltext in Publisher |