Long noncoding RNA Smyca coactivates TGF-β/Smad and Myc pathways to drive tumor progression

Long noncoding RNA Smyca coactivates TGF-β/Smad and Myc pathways to drive tumor progression

Background: Metastasis and chemoresistance are major culprits of cancer mortality, but factors contributing to these processes are incompletely understood. Methods: Bioinformatics methods were used to identify the relations of Smyca expression to clinicopathological features of human cancers. RNA-se...

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Bibliographic Details
Main Authors: Chan, S.-J (Author), Chen, H.-Y (Author), Chen, R.-H (Author), Chen, Y. (Author), Chiang, S.-Y (Author), Hsiao, P.-W (Author), Huang, K.-W (Author), Jian, R.-I (Author), Jou, Y.-S (Author), Kao, Y.-T (Author), Lang, Y.-D (Author), Liao, C.-C (Author), Liu, X. (Author), Luan, C.-L (Author), Shih, J.-H (Author), Wei, A.-C (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Chemoresistance
c-Myc
EMT
LncRNA
Metastasis
Smad
TGF-β
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