Interleukin-6 mediated inflammasome activation promotes oral squamous cell carcinoma progression via JAK2/STAT3/Sox4/NLRP3 signaling pathway

Background: Interleukin-6 (IL-6) has been reported to be critical in oral squamous cell carcinoma (OSCC). However, the set of pathways that IL-6 might activate in OSCC are not fully understood. Methods: IL-6 and Sox4 expressions were first determined with RT-qPCR, ELISA, Western blot, or immunohisto...

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Bibliographic Details
Main Authors: Cao, P. (Author), Fei, W. (Author), Li, X. (Author), Liu, Y. (Author), Tang, N. (Author), Xiao, L. (Author), Zhou, H. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
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