Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidence

Human aromatase is a member of the cytochrome P450 superfamily, involved in steroid hormones biosynthesis. In particular, it converts androgen into estrogens being therefore responsible for the correct sex steroids balance. Due to its capacity in producing estrogens it has also been considered as a...

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Bibliographic Details
Main Authors: Castrignanò, S. (Author), Di Nardo, G. (Author), Di Paola, L. (Author), Di Venere, A. (Author), Gilardi, G. (Author), Mei, G. (Author), Nicolai, E. (Author), Zhang, C. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
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