Long non-coding RNA SNHG8 enhances triple-negative breast cancer cell proliferation and migration by regulating the miR-335-5p/PYGO2 axis

Long non-coding RNA SNHG8 enhances triple-negative breast cancer cell proliferation and migration by regulating the miR-335-5p/PYGO2 axis

Background: Growing evidence has demonstrated that long non-coding RNAs (lncRNAs) can function as modulators in the development of triple-negative breast cancer (TNBC). However, the function of lncRNA small nucleolar RNA host gene 8 (SNHG8) in TNBC remains unclear. Therefore, our study aimed at inve...

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Bibliographic Details
Main Authors: Jia, W. (Author), Lei, X. (Author), Li, J. (Author), Li, W. (Author), Qian, J. (Author), Shi, J. (Author), Sun, Y. (Author), Tang, T. (Author), Zhang, L. (Author), Zhang, S. (Author), Zheng, L. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Cell Line, Tumor
cell proliferation
Cell Proliferation
gene expression regulation
Gene Expression Regulation, Neoplastic
genetics
human
Humans
Intracellular Signaling Peptides and Proteins
long noncoding RNA SNHG8, human
long untranslated RNA
metabolism
microRNA
MicroRNAs
miR-335-5p
MIRN335 microRNA, human
PYGO2
PYGO2 protein, human
RNA, Long Noncoding
signal peptide
SNHG8
triple negative breast cancer
Triple Negative Breast Neoplasms
Triple-negative breast cancer
tumor cell line
upregulation
Up-Regulation
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