Increasing lipid yield in Yarrowia lipolytica through phosphoketolase and phosphotransacetylase expression in a phosphofructokinase deletion strain

Increasing lipid yield in Yarrowia lipolytica through phosphoketolase and phosphotransacetylase expression in a phosphofructokinase deletion strain

Background: Lipids are important precursors in the biofuel and oleochemical industries. Yarrowia lipolytica is among the most extensively studied oleaginous microorganisms and has been a focus of metabolic engineering to improve lipid production. Yield improvement, through rewiring of the central ca...

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Bibliographic Details
Main Authors: Chen, S. (Author), Chifamba, G. (Author), Consiglio, A.L (Author), Kamineni, A. (Author), MacEwen, K. (Author), Shaw, A.J (Author), Tsakraklides, V. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
biofuel
Carbon
carbon flux
Cell-specific lipid productivity
Central carbon metabolism
Central carbon metabolisms
enzyme activity
fungus
Glucose
lipid
Lipid accumulations
Lipid yield
Metabolic engineering
Metabolism
Microbial biocatalysts
microorganism
Oleaginous microorganisms
Oleochemical industry
Pentose phosphate pathway
Phosphoketolase
Phosphotransacetylase
photosynthesis
Productivity
Specific productivity
Strain
Yarrowia lipolytica
yield response
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