Hybrid promoter engineering strategies in Yarrowia lipolytica: isoamyl alcohol production as a test study

Hybrid promoter engineering strategies in Yarrowia lipolytica: isoamyl alcohol production as a test study

Background: In biological cells, promoters drive gene expression by specific binding of RNA polymerase. They determine the starting position, timing and level of gene expression. Therefore, rational fine-tuning of promoters to regulate the expression levels of target genes for optimizing biosyntheti...

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Bibliographic Details
Main Authors: Foo, J.L (Author), Liu, S. (Author), Lu, Z. (Author), Wang, S. (Author), Xiao, D. (Author), Yu, A. (Author), Zhang, C. (Author), Zhao, B. (Author), Zhao, Y. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
alcohol
Biochemistry
biofuel
Biosynthesis
Biosynthesis pathways
Biosynthetic pathway
cellulose
Gene expression
Hybrid promoter
Isoamyl alcohol
Metabolic engineering
Metabolic pathways
metabolism
Metabolism
Platform chemicals
Promoter elements
Promoter strength
RNA
Saccharomyces cerevisiae
Strain improvement
strategic approach
Synthetic promoter
Y. lipolytica
Yarrowia lipolytica
Yeast
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