Rational engineering of Saccharomyces cerevisiae towards improved tolerance to multiple inhibitors in lignocellulose fermentations

Rational engineering of Saccharomyces cerevisiae towards improved tolerance to multiple inhibitors in lignocellulose fermentations

Background: The fermentation of lignocellulose hydrolysates to ethanol requires robust xylose-capable Saccharomycescerevisiae strains able to operate in the presence of microbial inhibitory stresses. This study aimed at developing industrial S.cerevisiae strains with enhanced tolerance towards pretr...

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Bibliographic Details
Main Authors: Brandt, B.A (Author), García-Aparicio, M.D.P (Author), Görgens, J.F (Author), van Zyl, W.H (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
bioengineering
Bioethanol
Biomass
cellulose
Cellulose
concentration (composition)
Cytology
Detoxification
Ecology
Economic and social effects
Elasticity
Ethanol
fermentation
Fermentation
Gene combinations
Genes
glucose
inhibition
inhibitor
Inhibitor tolerances
lignin
Lignin
Lignocellulose
Lignocellulose hydrolysates
membrane
Microbial inhibitors
Parental strains
Saccharomyces cerevisiae
Saccharomycescerevisiae
Spent sulphite liquor
Spent sulphite liquors
Sugarcane bagasse hydrolysate
Synthetic inhibitors
Xylose fermentation
yeast
Yeast
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