Engineering Escherichia coli for highly efficient production of lacto-N-triose II from N-acetylglucosamine, the monomer of chitin

Engineering Escherichia coli for highly efficient production of lacto-N-triose II from N-acetylglucosamine, the monomer of chitin

Background: Lacto-N-triose II (LNT II), an important backbone for the synthesis of different human milk oligosaccharides, such as lacto-N-neotetraose and lacto-N-tetraose, has recently received significant attention. The production of LNT II from renewable carbon sources has attracted worldwide atte...

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Bibliographic Details
Main Authors: Hu, D. (Author), Mu, W. (Author), Wu, H. (Author), Zhang, W. (Author), Zhu, Y. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
biofuel
chitin
Chitin
coliform bacterium
Deacetylase
E.coli cells
Environmental protection
enzyme activity
Enzymes
Epimerization
Escherichia coli
Feedstocks
gene expression
Gene expression
Glucosamine synthase
Human milk oligosaccharides
hydrolysis
Lacto-N-triose II
Lactose Hydrolysis
Metabolic engineering
metabolism
Metabolism
Monomers
N-Acetylglucosamine
Renewable carbon sources
Sustainable development
UDP-N-acetylglucosamine pyrophosphorylase
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