NFκB inhibition to lift the mechano-competence of mesenchymal stromal cell-derived neocartilage toward articular chondrocyte levels

Background: Fully functional regeneration of skeletal defects by multipotent progenitor cells requires that differentiating cells gain the specific mechano-competence needed in the target tissue. Using cartilage neogenesis as an example, we asked whether proper phenotypic differentiation of mesenchy...

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Bibliographic Details
Main Authors: Diederichs, S. (Author), Lückgen, J. (Author), Raqué, E. (Author), Reiner, T. (Author), Richter, W. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
BMP
Online Access:View Fulltext in Publisher