NFκB inhibition to lift the mechano-competence of mesenchymal stromal cell-derived neocartilage toward articular chondrocyte levels
Background: Fully functional regeneration of skeletal defects by multipotent progenitor cells requires that differentiating cells gain the specific mechano-competence needed in the target tissue. Using cartilage neogenesis as an example, we asked whether proper phenotypic differentiation of mesenchy...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |