Fibroblast growth factor receptor 4 promotes glioblastoma progression: a central role of integrin-mediated cell invasiveness

Fibroblast growth factor receptor 4 promotes glioblastoma progression: a central role of integrin-mediated cell invasiveness

Glioblastoma (GBM) is characterized by a particularly invasive phenotype, supported by oncogenic signals from the fibroblast growth factor (FGF)/ FGF receptor (FGFR) network. However, a possible role of FGFR4 remained elusive so far. Several transcriptomic glioma datasets were analyzed. An extended...

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Bibliographic Details
Main Authors: Berger, W. (Author), Distel, M. (Author), Donoghue, D.J (Author), Englinger, B. (Author), Erhart, F. (Author), Gabler, L. (Author), Gojo, J. (Author), Grasl-Kraupp, B. (Author), Grissenberger, S. (Author), Grusch, M. (Author), Jaunecker, C.N (Author), Katz, S. (Author), Kiesel, B. (Author), Kirchhofer, D. (Author), Laemmerer, A. (Author), LaFranca, M. (Author), Lang, A. (Author), Lötsch, D. (Author), Marian, B. (Author), Mayr, L. (Author), Mohr, T. (Author), Pirker, C. (Author), Schüler, J. (Author), Spiegl-Kreinecker, S. (Author), Stojanovic, M. (Author), Sturtzel, C. (Author), van Schoonhoven, S. (Author), Vician, P. (Author), Wenninger-Weinzierl, A. (Author), Woitzuck, V. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
FAK
FGF19
FGFR4
Glioblastoma
Integrins
Invasiveness
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