Modulation of synaptic plasticity, motor unit physiology, and TDP-43 pathology by CHCHD10

Modulation of synaptic plasticity, motor unit physiology, and TDP-43 pathology by CHCHD10

Mutations in CHCHD10, a gene coding for a mitochondrial intermembrane space protein, are associated with Frontotemporal dementia (FTD)-Amyotrophic lateral sclerosis (ALS) spectrum disorders, which are pathologically characterized by cytoplasmic inclusions containing TDP-43. FTD/ALS-linked CHCHD10 mu...

Full description

Bibliographic Details
Main Authors: Bukhari, M.Z (Author), Buosi, S.C (Author), Chacko, A. (Author), Ermekbaeva, A. (Author), Kang, D.E (Author), Kotsiviras, P. (Author), LePochat, P. (Author), Liu, T. (Author), Sista, A. (Author), Wang, X. (Author), Woo, J.-A.A (Author), Yan, Y. (Author), Zhao, X. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
CHCHD10
Frontotemporal dementia
Mitochondria
Synapse
TDP-43
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items